Spinosad: a naturally-occurring antiparasitic compound1

Unlike the systemically absorbed neurotoxic agents found in many of today’s over-the-counter (OTC) and prescription treatments, our active compound derives from a naturally occurring soil microorganism that targets parasites on or within the most superficial layer of the skin (stratum corneum).1

As a result, spinosad is proven to be a highly selective, environmentally friendly, and effective anti-parasitic compound with little or no evidence of toxicity or adverse events, and no known resistance in head lice.1,2,3

Mechanism of Action

Along with a highly sensitive and selective mechanism of action that differs from neurotoxic agents like permethrin and pyrethroids:

Spinosad, the active compound, is not systemically absorbed even in patients as young as six (6) months of age.1,2

References: 1. Data on file. 2. Natroba Prescribing Information. 3. DOW AgroSciences 2001.